TMAO is formed in the liver from trimethylamine (TMA), a substance produced by gut bacteria from food-based compounds such as choline, carnitine, lecithin, betaine, gamma-butyrobetaine, and ergothioneine
Weight typically returns gradually over 6-12 months after discontinuation because the underlying biological drivers of weight gain (hunger signals, insulin resistance, metabolic rate) return to baseline
Alfred Lohninger, H
Rahn, S., Zimmermann, V., Viol, F., Knaack, H., Stemmer, K., Peters, L., Lenk, L., Ungefroren, H., Saur, D., Schfer, H., et al
FIGURE 3 4 Application of nanoparticles to enhance the anti-cancer action of natural compounds Nanotechnology has emerged as a promising strategy to enhance the therapeutic potential of natural compounds in cancer treatment (Sell et al., 2023)
doi: 10.1681/asn.2025h7he3fr5 38 DuYWuMSongSBianYShiY